10 Experiments That Created Something Alive by Accident

These 10 experiments accidentally produced living organisms or life-like systems, changing scientific understanding.

  • Sophia Zapanta
  • 3 min read
10 Experiments That Created Something Alive by Accident
Yurii Kandurov, Ksenia Kandurova, Dmitry Stavtsev on Wikimedia Commons

Scientists sometimes make discoveries they did not expect, and some experiments have even produced life-like results. Accidental creation of living organisms or self-replicating systems has occurred in laboratories over the years. This article highlights 10 experiments where scientists inadvertently created something alive.

1. 1. Stanley Miller’s Primordial Soup Experiment

Wikimedia Commons

Wikimedia Commons

In 1953, Stanley Miller tried to recreate early Earth conditions. He applied electrical sparks to a mixture of gases to see if organic molecules would form. Unexpectedly, amino acids — the building blocks of life — were produced. This experiment provided the first evidence that life’s components could form naturally.

2. 2. Euglena in Laboratory Cultures

Doc. RNDr. Josef Reischig, CSc. on Wikimedia Commons

Doc. RNDr. Josef Reischig, CSc. on Wikimedia Commons

Researchers accidentally introduced light and nutrients in ways that encouraged Euglena, a single-celled organism, to multiply rapidly. They did not intend to create new populations. The experiment highlighted how environmental changes could trigger unexpected life growth. It showed how life can flourish under favorable conditions.

3. 3. Yeast Mutations Producing New Strains

Morganocyte on Wikimedia Commons

Morganocyte on Wikimedia Commons

Yeast cultures in fermentation experiments sometimes mutated spontaneously. Scientists noticed these accidental mutations led to new strains with unique properties. These strains were alive and could reproduce independently. Such discoveries advanced understanding of microbial evolution.

4. 4. Slime Mold Networking

Red58bill on Wikimedia Commons

Red58bill on Wikimedia Commons

Slime molds were used in experiments to study decision-making and movement. Researchers accidentally observed them forming complex, adaptive networks. The molds showed unexpected intelligence and problem-solving abilities. This challenged traditional ideas about simple life forms.

5. 5. Bacteria Developing Antibiotic Resistance

CDC/James Gathany on Wikimedia Commons

CDC/James Gathany on Wikimedia Commons

Experiments studying bacterial growth led to the accidental evolution of antibiotic-resistant strains. Scientists did not plan for this adaptation. These bacteria survived and reproduced in environments lethal to other strains. The experiments revealed how life can adapt quickly under pressure.

6. 6. Artificial Vesicles Mimicking Cells

Internet Archive Book Images on Wikimedia Commons

Internet Archive Book Images on Wikimedia Commons

Chemists created lipid vesicles to study membranes. By accident, some vesicles began growing and dividing like simple cells. These vesicles were not alive in the full sense but displayed life-like behavior. They helped scientists understand how early cells may have formed.

7. 7. RNA Self-Replication Experiments

Phacelias on Wikimedia Commons

Phacelias on Wikimedia Commons

Laboratory tests with RNA molecules sometimes produced sequences capable of replicating themselves. This replication was not intended in the original experiments. The molecules exhibited a key feature of living systems. These experiments provided insight into the origins of life.

8. 8. Predator-Prey Microbe Experiments

James St. John on Wikimedia Commons

James St. John on Wikimedia Commons

Microbial experiments designed to study populations occasionally led to new interactions. Some microbes evolved behaviors mimicking predation and symbiosis. These emergent relationships were not planned. The experiments demonstrated how life can evolve complexity spontaneously.

9. 9. Cyanobacteria Producing Oxygen

Lamiot on Wikimedia Commons

Lamiot on Wikimedia Commons

Early lab cultures of cyanobacteria produced oxygen as a byproduct. Researchers initially focused on growth, not on environmental impact. The oxygen changed the culture conditions drastically. This accidental outcome mirrored processes that shaped Earth’s atmosphere.

10. 10. Laboratory-Bred Paramecia

Picturepest on Wikimedia Commons

Picturepest on Wikimedia Commons

Paramecia used in feeding and reproduction studies sometimes displayed unexpected cooperative behavior. Scientists did not anticipate these life-like interactions. The organisms adapted to laboratory conditions in novel ways. These findings illustrate the complexity of even simple life forms.

Written by: Sophia Zapanta

Sophia is a digital PR writer and editor who specializes in crafting content that boosts brand visibility online. A lifelong storyteller and curious observer of human behavior, she’s written on everything from online dating to tech’s impact on daily life. When she’s not writing, Sophia dives into social media trends, binges on K-dramas, or devours self-help books like The Mountain is You, which inspired her to tackle life’s challenges head-on.

Recommended for You