10 Experiments Scientists Regret Doing

This listicle highlights 10 experiments that, in hindsight, are widely condemned for their moral violations, ranging from psychological manipulation to medical abuse.

  • Daisy Montero
  • 4 min read
10 Experiments Scientists Regret Doing
Artem Podrez on Pexels

Scientists have pushed for new discoveries over the years, and some of their choices caused real harm. These experiments led to strict rules on how research should be done. Their history shows that curiosity without care can hurt people in lasting ways.

1. 1. Milgram Obedience Experiment

Fred the Oyster on Wikimedia Commons

Fred the Oyster on Wikimedia Commons

The Milgram Obedience Experiment showed how far people would follow instructions even when they believed they were hurting someone. Many volunteers felt intense stress because they thought they were delivering real electric shocks. The emotional pressure stayed with some participants long after the study ended. Milgram later expressed concerns about the impact of the experiment and how deeply it affected the people involved.

2. 2. Stanford Prison Experiment

Eric. E. Castro on Wikimedia Commons

Eric. E. Castro on Wikimedia Commons

The Stanford Prison Experiment turned into chaos as soon as students stepped into their roles as guards and prisoners. Some guards became abusive, and several prisoners showed real signs of emotional distress. The study was shut down early due to unsafe conditions. It remains one of the strongest examples of how quickly people can misuse power when given authority.

3. 3. Tuskegee Syphilis Study

Centers for Disease Control and Prevention on Wikimedia Commons

Centers for Disease Control and Prevention on Wikimedia Commons

The Tuskegee Syphilis Study followed Black men with untreated syphilis without telling them the truth. Many believed they were receiving help, but they were denied real medical care, even when treatment finally existed. Families suffered for years because of the choices made by the researchers. This study became a turning point that changed medical ethics in the United States.

4. 4. Project MKULTRA

Central Intelligence Agency on Wikimedia Commons

Central Intelligence Agency on Wikimedia Commons

Project MKULTRA tested drugs and psychological methods on people who often did not know what was happening. Some subjects experienced fear, confusion, and long-lasting mental effects. The secrecy around the program added even more concern once the details became public. It is remembered as a major failure in respecting human rights during research.

5. 5. Willowbrook Hepatitis Study

Scan by NYPL on Wikimedia Commons

Scan by NYPL on Wikimedia Commons

Doctors at Willowbrook State School exposed children to hepatitis so they could study how the disease spread. Many of the children did not understand what was being done to them, and families were pressured to agree. The conditions at the school were already poor, making the study even more troubling. It now stands as a clear example of research that ignored the safety of vulnerable people.

6. 6. Little Albert Experiment

Vibha C Kashyap on Wikimedia Commons

Vibha C Kashyap on Wikimedia Commons

The Little Albert Experiment conditioned a young child to fear animals by pairing them with loud noises. The boy started showing fear not just toward the rat but also toward other furry objects. The researchers never attempted to reverse the fear they created. The study is often cited as an unethical approach to understanding human behavior.

7. 7. Holmesburg Prison Experiments

Marduk on Wikimedia Commons

Marduk on Wikimedia Commons

At Holmesburg Prison, inmates were used in dermatology tests involving chemicals and drugs. Many prisoners were not fully informed about the risks or long-term effects. The tests caused fear and distrust among those who lived through them. The experiment is now viewed as a major violation of consent within medical research.

8. 8. Fe 59 Radiation Study

reyhan diptayana on Pexels

reyhan diptayana on Pexels

The Fe 59 Radiation Study gave immigrant women radioactive iron to observe how their bodies absorbed it. Many of them did not understand the full purpose of the study or the dangers involved. Researchers prioritized data collection over patient safety. The study is now used as a lesson on the need for clear and honest consent in medical research.

9. 9. Psychic Driving

Jonathan Cooper on Pexels

Jonathan Cooper on Pexels

Psychic Driving attempted to change patients by exposing them to repeated recorded messages. Some were also given strong medications and heavy electroshock sessions. The combination left many patients confused, distressed, and unable to return to normal routines. The doctor behind the work later faced major criticism for the harm the treatment caused.

10. 10. Project Artichoke

Keith Evans on Wikimedia Commons

Keith Evans on Wikimedia Commons

Project Artichoke explored how drugs and hypnosis might influence a person’s behavior. Test subjects were sometimes pushed into highly stressful situations without proper consent. The program raised many questions about how far government research should go. It remains one of the most unsettling efforts from the early Cold War period.

Written by: Daisy Montero

Daisy began her career as a ghost content editor before discovering her true passion for writing. After two years, she transitioned to creating her own content, focusing on news and press releases. In her free time, Daisy enjoys cooking and experimenting with new recipes from her favorite cookbooks to share with friends and family.

Recommended for You

15 Dangerous Experiments That Changed Science

15 Dangerous Experiments That Changed Science

Some of the most important breakthroughs in science came from experiments that were extremely dangerous.

20 Weirdest Experiments Ever Conducted on Humans

20 Weirdest Experiments Ever Conducted on Humans

This is a chilling journey through history’s most bizarre and unethical human experiments, revealing the dark side of scientific curiosity and the haunting consequences of pushing ethical boundaries.